“Metastatic Urothelial Carcinoma Pipeline Insight, 2023” report by DelveInsight outlines a comprehensive assessment of the present clinical/non-clinical development activities and growth prospects across the Metastatic Urothelial Carcinoma Market.
The Metastatic Urothelial Carcinoma Pipeline report embraces in-depth commercial, regulatory, and Metastatic Urothelial Carcinoma clinical trial assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the emerging Metastatic Urothelial Carcinoma drugs, including the mechanism of action, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers, acquisition, funding, designations, and other product-related details.
Metastatic Urothelial Carcinoma Pipeline Analysis
The report provides insights into:
The report provides detailed insights into the emerging therapies for Metastatic Urothelial Carcinoma treatment and the aggregate therapies developed by major pharma companies.
It accesses the different Metastatic Urothelial Carcinoma therapies segmented into early-stage, mid-stage, and late-stage clinical development.
It outlines the major Metastatic Urothelial Carcinoma companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
The report evaluates the Metastatic Urothelial Carcinoma drugs that are under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
It navigates the major collaborations (company-company collaborations and company-academia collaborations), licensing agreements, financing details, data presentation by the pharma giants, and regulatory approval in the Metastatic Urothelial Carcinoma therapeutic market.
Metastatic Urothelial Carcinoma Therapeutics Landscape
Urothelial Carcinoma, also known as transitional cell carcinoma (TCC), is characterized by cancer beginning in the urothelial cells lining the bladder, it is one of the most common forms of bladder cancer (BC). Treatment for metastatic form of Urothelial Carcinoma (UC) can be employed in different classes of chemotherapy, immunotherapy, radiation therapy, target-specific therapy, and surgical treatment. Metastatic Urothelial Carcinoma has shown poor survival when treated with chemotherapy; however, due to the advancements in the treatment of new immunotherapies, more alternatives are available.
Chemotherapy majorly forms the first line of treatment, mainly comprising platinum-based products. Cisplatin-based chemotherapy is a chief product in the list of chemotherapeutics. The commonly used cisplatin regimens include MVAC (methotrexate, vinblastine, doxorubicin, cisplatin) or GC (gemcitabine and cisplatin). Cisplatin is followed by Carboplatin for therapeutic regimens, such as M-CAVI (methotrexate, carboplatin, and vinblastine). A few nonplatinum regimens include gemcitabine with a taxane (either paclitaxel or docetaxel) rather than platinum. Single-agent chemotherapy also holds importance in the treatment routine, including Gemcitabine, Vinflunine, and Ifosfamide.
The major class of treatment also comprises Immunotherapy, which helps the patient’s own immune system to recognize and destroy cancer cells. Developments in this domain have led to the development of immune checkpoint inhibitors (ICIs) targeting the programmed death (PD-1/PDL-1) pathway. Immunotherapy is used in platinum ineligible or refractory cases. The market holds Atezolizumab (Tecentriq), Pembrolizumab (Keytruda), Nivolumab (Opdivo), Durvalumab (Imfinzi), and Avelumab (Bavencio) as approved products targeting PD-1/PDL-1 pathway.
There are approx. 40+ key companies developing therapies for Metastatic Urothelial Carcinoma. Currently, PharmaMar is leading the therapeutics market with its Metastatic Urothelial Carcinoma drug candidates in the most advanced stage of clinical development.
Metastatic Urothelial Carcinoma Companies Actively Working in the Therapeutic Market Include:
PharmaMar
Ectin Research AG
Exelixis
Eli Lilly and Company
Merck Sharp & Dohme LLC
Astellas Pharma Inc
Seagen Inc.
Shanghai Miracogen Inc.
Advaxis, Inc.
And Many Others
Emerging and Marketed Metastatic Urothelial Carcinoma Drugs Covered in the Report Include:
MFA 370: Ectin Research AG
XL 092: Exelixis
Lurbinectedin: PharmaMar
Ramucirumab: Eli Lilly
Infigratinib: QED Therapeutics
Rogaratinib: Bayer
Pemigatinib: Incyte Corporation
Sacituzumab govitecan: Immunomedics
NKTR-214: Nektar Therapeutics/Bristol-Myers Squibb
RX-3117: Rexahn Pharmaceuticals
And Many More
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Analysis of Emerging Metastatic Urothelial Carcinoma Therapies by Phases
The report covers the emerging products under different phases of clinical development like –
Late-stage products (Phase III)
Mid-stage products (Phase II)
Early-stage products (Phase I)
Pre-clinical and Discovery stage candidates
Discontinued and inactive candidates
Route of Administration
Metastatic Urothelial Carcinoma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
Intra-articular
Intraocular
Intrathecal
Intravenous
Ophthalmic
Oral
Parenteral
Subcutaneous
Topical
Transdermal
Molecule Type
Products have been categorized under various Molecule types such as
Oligonucleotide
Peptide
Small molecule
Learn How the Metastatic Urothelial Carcinoma Treatment Outlook will Evolve with the Ongoing Clinical and commercial Activities in the Therapeutic Market @
Table of Content (TOC)
1. Report Introduction
2. Executive Summary
3. Metastatic Urothelial Carcinoma Treatment Patterns
4. Metastatic Urothelial Carcinoma – DelveInsight’s Analytical Perspective
5. Therapeutic Assessment
6. Metastatic Urothelial Carcinoma Late Stage Products (Phase-III)
7. Metastatic Urothelial Carcinoma Mid-Stage Products (Phase-II)
8. Metastatic Urothelial Carcinoma Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Metastatic Urothelial Carcinoma Discontinued Products
13. Metastatic Urothelial Carcinoma Product Profiles
14. Major Metastatic Urothelial Carcinoma Companies in the Market
15. Key Products in the Metastatic Urothelial Carcinoma Therapeutics Segment
16. Dormant and Discontinued Products
17. Metastatic Urothelial Carcinoma Unmet Needs
18. Metastatic Urothelial Carcinoma Future Perspectives
19. Metastatic Urothelial Carcinoma Analyst Review
20. Appendix
21. Report Methodology
*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.
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About DelveInsight
DelveInsight is a leading Business Consultant and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.
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